March 29, 2026
Abiye Tigabu Molla at Asia-Pacific Biofilms 2026
Accepted abstract title
Unravelling Novel Resistance Genes, Virulence Factors, and Therapeutic Targets in Multidrug-Resistant Pseudomonas aeruginosa Isolates.
A brief description of poster or talk This study investigated antimicrobial resistance, virulence factors, and biofilm formation in P. aeruginosa ocular isolates using MIC testing, crystal violet assay, whole-genome sequencing, and RNA sequencing. One-third of the isolates were multidrug-resistant (MDR), and all MDR isolates were strong biofilm producers. MDR strains possessed unique resistance genes and tested positive for exoU, whereas non-MDR isolates tested positive for exoS. Genomic and transcriptomic analyses identified increased variation and upregulated genes related to resistance, stress response, and quorum sensing. These findings highlight potential targets for improved treatment strategies.
A short reflection on your conference experience The conference was very interesting and focused on biofilm-related infections, including diagnostic approaches and intervention strategies to tackle biofilm formation. Researchers from diverse backgrounds shared their findings, providing valuable insights and broadening my understanding of the field.
